Well, there exists a directory "~/.config/unity3d/IntravenousSoftware/NeonXSZ" and it includes a "prefs" file that contains the resolution options.
However changing those only affects the splash screen and the resolution seems to default to the old value of 1920x1080 when you get into the game (i.e. the part with the terms and conditions pops up but there are still no visible buttons and I cannot use my mouse to scroll the contents), regardless of what's in the prefs file. (the values in the prefs file default back to 1920x1080; you can change the permissions to read only but that has no effect on the game itself, it just means that the splash screen will keep the resolution specified in this file since it fails to overwrite them).
[edit]
Btw. I am using Debian and when I installed the game I wasn't able to launch it from desura because "desura/common/neonxsz/NeonXSZ" wasn't marked as executable, just fyi. :)
Daidalos
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